Use formal titles and surnames when first addressing people in Switzerland, especially in business, official settings, and with older people, and wait to be invited to use first names. In German-speaking areas
Herr and
Frau are standard, while in French- and Italian-speaking regions
Monsieur,
Madame, and
Signore/Signora are used, and people generally appreciate a polite, reserved tone rather than overly familiar greetings.